研究成果-2020
Shun Shi, Shuangjiang Yu, Gao Li*, Chaoliang He*, Xuesi Chen. Biocompatible in situ-forming glycopolypeptide hydrogels. Science China Technological Sciences 2020, 63(6), 992-1004.
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Shun Shi, Shuangjiang Yu, Gao Li*, Chaoliang He*, Xuesi Chen. Biocompatible in situ-forming glycopolypeptide hydrogels. Science China Technological Sciences 2020, 63(6), 992-1004.
Zhen Zhang , Chaoliang He *, and Xuesi Chen * , Injectable Click Polypeptide Hydrogels via Tetrazine-Norbornene Chemistry for Localized Cisplatin Release . Polymers 2020, 12, 884 ;
Qiang Lv, Shuangjiang Yu, Fenli Quan, Chaoliang He*, Xuesi Chen*. Thermosensitive polypeptide hydrogels co-loaded with two anti-tumor agents to reduce multi-drug resistance and enhance local tumor treatment. Advanced Therapeutics 2020, 3...
Shuangjiang Yu, Shu Wei, Liang Liu, Desheng Qi, Jiayu Wang, Guojun Chen, Wanying He, Chaoliang He*, Xuesi Chen, Zhen Gu*. Enhanced local cancer therapy using a CA4P and CDDP co-loaded polypeptide gel depot. Biomaterials Science 2019, 7(3...
Shuangjiang Yu, Chao Wang, Jicheng Yu, Jinqiang Wang, Yue Lu, Yuqi Zhang, Xudong Zhang, Quanyin Hu, Wujin Sun, Chaoliang He*, Xuesi Chen*, Zhen Gu*. Injectable bioresponsive gel depot for enhanced immune checkpoint blockade. Advanced Material...
Qiang Lv, Chaoliang He*, Fenli Quan, Shuangjiang Yu, Xuesi Chen. DOX/IL-2/IFN-γ co-loaded thermo-sensitive polypeptide hydrogel for efficient melanoma treatment. Bioactive Materials 2018, 3, 118-128.
Liang Liu, Ying Zhang, Shuangjiang Yu, Zhen Zhang, Chaoliang He*, Xuesi Chen*. pH- and amylase-responsive carboxymethyl starch/poly(2-isobutyl-acrylic acid) hybrid microgels as effective enteric carriers for oral insu...
Liang Liu, Ying Zhang, Shuangjiang Yu, Zhiming Yang, Chaoliang He*, Xuesi Chen*. Dual stimuli-responsive nanoparticle-incorporated hydrogels as an oral insulin carrier for intestine-targeted delivery and enhanced para...
Shuangjiang Yu, Chaoliang He*, Xuesi Chen. Injectable hydrogels as unique platforms for local chemotherapeutics‐based combination antitumor therapy. Macromolecular Bioscience 2018, 18(12), 1800240.
Zhen Zhang, Chaoliang He*, Xuesi Chen*. Hydrogels based on pH-responsive reversible carbon–nitrogen double-bond linkages for biomedical applications. Materials Chemistry Frontiers 2018, 2(10), 1765-1778.
Yilong Cheng, Chaoliang He*, Kaixuan Ren, Yan Rong, Chunsheng Xiao, Jianxun Ding, Xiuli Zhuang, Xuesi Chen*. Injectable enzymatically cross-linked hydrogels with light-controlled degradation profile. Macromolecular Rapid Communications&n...
Xilong Wu, Yundi Wu, Hongbo Ye, Shuangjiang Yu, Chaoliang He*, Xuesi Chen*. Interleukin-15 and cisplatin co-encapsulated thermosensitive polypeptide hydrogels for combined immuno-chemotherapy. Journal of Controlled Release 2017, 255, 81-...
Shuangjiang Yu, Dianliang Zhang, Chaoliang He*, Wujin Sun, Rangjuan Cao, Shusen Cui, Mingxiao Deng, Zhen Gu*, Xuesi Chen*. Injectable Thermo-Sensitive Polypeptide-based CDDP-Complexed Hydrogel for Improving Localized Antitumor Efficacy. Bioma...
Kaixuan Ren, Bin Li, Qinghua Xu, Chunsheng Xiao, Chaoliang He*, Gao Li*, Xuesi Chen. Enzymatically Crosslinked Hydrogels based on Linear Poly(ethylene glycol) Polymer: Performance and Mechanism. Polymer Chemistry 2017, 8(45), 7017-7024.
Qinghua Xu, Zhen Zhang, Chunsheng Xiao, Chaoliang He*, Xuesi Chen*. Injectable polypeptide hydrogel as biomimetic scaffolds with tunable bioactivity and controllable cell adhesion. Biomacromolecules 2017, 18 (4), 1411-1418.
Chaoliang He, Zhaohui Tang, Huayu Tian, Xuesi Chen*. Co-delivery of chemotherapeutics and proteins for synergistic therapy. Advanced Drug Delivery Reviews 2016, 98, 64-76.
Xilong Wu, Chaoliang He*, Yundi Wu, Xuesi Chen*. Synergistic therapeutic effects of Schiff's base cross-linked injectable hydrogels for local co-delivery of metformin and 5-fluorouracil in a mouse colon carcinoma model. Biomaterials 2016, 75,...
Qinghua Xu, Chaoliang He*, Zhen Zhang, Kaixuan Ren, Xuesi Chen*. Injectable, biomolecule-responsive polypeptide hydrogels for cell encapsulation and facile cell recovery through triggered degradation. ACS Applied Materials & Interfaces&nb...
Kaixuan Ren, Haitao Cui, Qinghua Xu, Chaoliang He*, Gao Li*, Xuesi Chen. Injectable polypeptide hydrogels with tunable microenvironment for 3D spreading and chondrogenic differentiation of bone marrow-derived mesenchymal stem cells. Biomacrom...
Qinghua Xu, Chaoliang He*, Kaixuan Ren, Chunsheng Xiao, Xuesi Chen*. Thermosensitive polypeptide hydrogels as a platform for ROS-triggered cargo release with innate cytoprotective ability under oxidative stress. Advanced Healthcare Materials&...