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Dong Li#, Shun Shi#, Dan Zhao, Yan Rong, Yuhao Zhou, Junfeng Ding, Chaoliang He*, Xuesi Chen*. Effect of polymer topology and residue chirality on biodegradability of polypeptide hydrogels. ACS Biomaterials Science & Engineering 2022, 8(2...
Dong Li, Dan Zhao, Chaoliang He*, Xuesi Chen*. Crucial impact of residue chirality on the gelation process and biodegradability of thermoresponsive polypeptide hydrogels. Biomacromolecules 2021, 22(9), 3992-4003. DOI:10.1021/acs.biomac.1c007...
Dan Zhao, Dong Li, Fenli Quan, Yuhao Zhou, Zhen Zhang, Xuesi Chen, Chaoliang He*. Rapidly Thermoreversible and Biodegradable Polypeptide Hydrogels with Sol–Gel–Sol Transition Dependent on Subtle Manipulation of Side Groups. Biomacromolecules...
Yue Cao, Yuhao Zhou, Zhixiong Chen, Zhen Zhang, Xuesi Chen, Chaoliang He*. Localized chemotherapy based on injectable hydrogel boosts the antitumor activity of adoptively transferred T lymphocytes in vivo. Advanced Healthcare Materials 2021,...
Yuhao Zhou, Zhixiong Chen, Dan Zhao, Dong Li, Chaoliang He*, Xuesi Chen*. A pH-triggered self-unpacking capsule containing zwitterionic hydrogel-coated MOF nanoparticles for efficient oral exendin-4 delivery. Advanced Materials 2021, 33, 2102...
Yingge Shi, Dong Li, Junfeng Ding, Chaoliang He*, Xuesi Chen. Physiologically relevant pH- and temperature-responsive polypeptide hydrogels with adhesive properties. Polymer Chemistry 2021, DOI: 10.1039/d1py00290b.
Shun Shi, Jiayu Wang, Tianran Wang, Hui Ren, Yuhao Zhou, Gao Li, Chaoliang He*, Xuesi Chen. Influence of residual chirality on the conformation and enzymatic degradation of glycopolypeptide based biomaterials. Science China Technological Scie...
Yingge Shi, Dong Li, Chaoliang He*, Xuesi Chen. Design of an injectable polypeptide hydrogel depot containing the immune checkpoint blocker anti-PD-L1 and doxorubicin to enhance antitumor combination therapy. Macromolecular Bioscience 20...
Hongyu Ma, Chaoliang He*, Xuesi Chen. Injectable hydrogels as local depots at tumor sites for antitumor immunotherapy and immune-based combination therapy. Macromolecular Bioscience 2021, 21, 2100039.
Zhen Zhang, Chaoliang He*, Yan Rong, Hui Ren, Tianran Wang, Zheng, Zou, Xuesi Chen*. A fast and versatile cross-linking strategy via o-phthalaldehyde condensation for mechanically strengthened and functional hydrogels. National Science ...
Yuhao Zhou, Liang Liu, Yue Cao, Shuangjiang Yu, Chaoliang He*, Xuesi Chen*. A nanocomposite vehicle based on metal-organic framework nanoparticle incorporated biodegradable microspheres for enhanced oral insulin delivery. ACS Applied Materia...
Yan Rong, Zhen Zhang, Chaoliang He*, Xuesi Chen. Bioactive polypeptide hydrogels modified with RGD and N-cadherin mimetic peptide promote chondrogenic differentiation of bone marrow mesenchymal stem cells. Science China Chemistry 2020 , 63...
Shun Shi, Shuangjiang Yu, Gao Li*, Chaoliang He*, Xuesi Chen. Biocompatible in situ-forming glycopolypeptide hydrogels. Science China Technological Sciences 2020, 63(6), 992-1004.
Zhen Zhang , Chaoliang He *, and Xuesi Chen * , Injectable Click Polypeptide Hydrogels via Tetrazine-Norbornene Chemistry for Localized Cisplatin Release . Polymers 2020, 12, 884 ;
Qiang Lv, Shuangjiang Yu, Fenli Quan, Chaoliang He*, Xuesi Chen*. Thermosensitive polypeptide hydrogels co-loaded with two anti-tumor agents to reduce multi-drug resistance and enhance local tumor treatment. Advanced Therapeutics 2020, 3...
Shuangjiang Yu, Shu Wei, Liang Liu, Desheng Qi, Jiayu Wang, Guojun Chen, Wanying He, Chaoliang He*, Xuesi Chen, Zhen Gu*. Enhanced local cancer therapy using a CA4P and CDDP co-loaded polypeptide gel depot. Biomaterials Science 2019, 7(3...
Shuangjiang Yu, Chao Wang, Jicheng Yu, Jinqiang Wang, Yue Lu, Yuqi Zhang, Xudong Zhang, Quanyin Hu, Wujin Sun, Chaoliang He*, Xuesi Chen*, Zhen Gu*. Injectable bioresponsive gel depot for enhanced immune checkpoint blockade. Advanced Material...
Qiang Lv, Chaoliang He*, Fenli Quan, Shuangjiang Yu, Xuesi Chen. DOX/IL-2/IFN-γ co-loaded thermo-sensitive polypeptide hydrogel for efficient melanoma treatment. Bioactive Materials 2018, 3, 118-128.
Liang Liu, Ying Zhang, Shuangjiang Yu, Zhen Zhang, Chaoliang He*, Xuesi Chen*. pH- and amylase-responsive carboxymethyl starch/poly(2-isobutyl-acrylic acid) hybrid microgels as effective enteric carriers for oral insu...
Liang Liu, Ying Zhang, Shuangjiang Yu, Zhiming Yang, Chaoliang He*, Xuesi Chen*. Dual stimuli-responsive nanoparticle-incorporated hydrogels as an oral insulin carrier for intestine-targeted delivery and enhanced para...