研究成果-2021
Yingge Shi, Dong Li, Junfeng Ding, Chaoliang He*, Xuesi Chen. Physiologically relevant pH- and temperature-responsive polypeptide hydrogels with adhesive properties. Polymer Chemistry 2021, DOI: 10.1039/d1py00290b.
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Yingge Shi, Dong Li, Junfeng Ding, Chaoliang He*, Xuesi Chen. Physiologically relevant pH- and temperature-responsive polypeptide hydrogels with adhesive properties. Polymer Chemistry 2021, DOI: 10.1039/d1py00290b.
Shun Shi, Jiayu Wang, Tianran Wang, Hui Ren, Yuhao Zhou, Gao Li, Chaoliang He*, Xuesi Chen. Influence of residual chirality on the conformation and enzymatic degradation of glycopolypeptide based biomaterials. Science China Technological Scie...
Yingge Shi, Dong Li, Chaoliang He*, Xuesi Chen. Design of an injectable polypeptide hydrogel depot containing the immune checkpoint blocker anti-PD-L1 and doxorubicin to enhance antitumor combination therapy. Macromolecular Bioscience 20...
Hongyu Ma, Chaoliang He*, Xuesi Chen. Injectable hydrogels as local depots at tumor sites for antitumor immunotherapy and immune-based combination therapy. Macromolecular Bioscience 2021, 21, 2100039.
Zhen Zhang, Chaoliang He*, Yan Rong, Hui Ren, Tianran Wang, Zheng, Zou, Xuesi Chen*. A fast and versatile cross-linking strategy via o-phthalaldehyde condensation for mechanically strengthened and functional hydrogels. National Science ...
Yuhao Zhou, Liang Liu, Yue Cao, Shuangjiang Yu, Chaoliang He*, Xuesi Chen*. A nanocomposite vehicle based on metal-organic framework nanoparticle incorporated biodegradable microspheres for enhanced oral insulin delivery. ACS Applied Materia...
Yan Rong, Zhen Zhang, Chaoliang He*, Xuesi Chen. Bioactive polypeptide hydrogels modified with RGD and N-cadherin mimetic peptide promote chondrogenic differentiation of bone marrow mesenchymal stem cells. Science China Chemistry 2020 , 63...
Shun Shi, Shuangjiang Yu, Gao Li*, Chaoliang He*, Xuesi Chen. Biocompatible in situ-forming glycopolypeptide hydrogels. Science China Technological Sciences 2020, 63(6), 992-1004.
Zhen Zhang , Chaoliang He *, and Xuesi Chen * , Injectable Click Polypeptide Hydrogels via Tetrazine-Norbornene Chemistry for Localized Cisplatin Release . Polymers 2020, 12, 884 ;
Qiang Lv, Shuangjiang Yu, Fenli Quan, Chaoliang He*, Xuesi Chen*. Thermosensitive polypeptide hydrogels co-loaded with two anti-tumor agents to reduce multi-drug resistance and enhance local tumor treatment. Advanced Therapeutics 2020, 3...
Shuangjiang Yu, Shu Wei, Liang Liu, Desheng Qi, Jiayu Wang, Guojun Chen, Wanying He, Chaoliang He*, Xuesi Chen, Zhen Gu*. Enhanced local cancer therapy using a CA4P and CDDP co-loaded polypeptide gel depot. Biomaterials Science 2019, 7(3...
Shuangjiang Yu, Chao Wang, Jicheng Yu, Jinqiang Wang, Yue Lu, Yuqi Zhang, Xudong Zhang, Quanyin Hu, Wujin Sun, Chaoliang He*, Xuesi Chen*, Zhen Gu*. Injectable bioresponsive gel depot for enhanced immune checkpoint blockade. Advanced Material...
Qiang Lv, Chaoliang He*, Fenli Quan, Shuangjiang Yu, Xuesi Chen. DOX/IL-2/IFN-γ co-loaded thermo-sensitive polypeptide hydrogel for efficient melanoma treatment. Bioactive Materials 2018, 3, 118-128.
Liang Liu, Ying Zhang, Shuangjiang Yu, Zhen Zhang, Chaoliang He*, Xuesi Chen*. pH- and amylase-responsive carboxymethyl starch/poly(2-isobutyl-acrylic acid) hybrid microgels as effective enteric carriers for oral insu...
Liang Liu, Ying Zhang, Shuangjiang Yu, Zhiming Yang, Chaoliang He*, Xuesi Chen*. Dual stimuli-responsive nanoparticle-incorporated hydrogels as an oral insulin carrier for intestine-targeted delivery and enhanced para...
Shuangjiang Yu, Chaoliang He*, Xuesi Chen. Injectable hydrogels as unique platforms for local chemotherapeutics‐based combination antitumor therapy. Macromolecular Bioscience 2018, 18(12), 1800240.
Zhen Zhang, Chaoliang He*, Xuesi Chen*. Hydrogels based on pH-responsive reversible carbon–nitrogen double-bond linkages for biomedical applications. Materials Chemistry Frontiers 2018, 2(10), 1765-1778.
Yilong Cheng, Chaoliang He*, Kaixuan Ren, Yan Rong, Chunsheng Xiao, Jianxun Ding, Xiuli Zhuang, Xuesi Chen*. Injectable enzymatically cross-linked hydrogels with light-controlled degradation profile. Macromolecular Rapid Communications&n...
Xilong Wu, Yundi Wu, Hongbo Ye, Shuangjiang Yu, Chaoliang He*, Xuesi Chen*. Interleukin-15 and cisplatin co-encapsulated thermosensitive polypeptide hydrogels for combined immuno-chemotherapy. Journal of Controlled Release 2017, 255, 81-...
Shuangjiang Yu, Dianliang Zhang, Chaoliang He*, Wujin Sun, Rangjuan Cao, Shusen Cui, Mingxiao Deng, Zhen Gu*, Xuesi Chen*. Injectable Thermo-Sensitive Polypeptide-based CDDP-Complexed Hydrogel for Improving Localized Antitumor Efficacy. Bioma...