gain
Tianran Wang, Junfeng Ding, Shuang Liang, Zhiqiang Lin, Jiaxuan Yang, Zhen Zhang, Zheng Zou, Gao Li, Xuesi Chen, Chaoliang He*. An adhesive immune-stimulating multifunctional hydrogel for potent tumor chemoimmunotherapy and postoperative woun...
Zhen Zhang, Chaoliang He*, Xuesi Chen*. Designing hydrogels for immunomodulation in cancer therapy and regenerative medicine. Advanced Materials 2024, 36, 2308894, DOI: 10.1002/adma.202308894.
Zheng Zou, Zhen Zhang, Hui Ren, Xueliang Cheng, Xuesi Chen, Chaoliang He*. Injectable antibacterial tissue-adhesive hydrogel based on biocompatible o-phthalaldehyde/amine crosslinking for efficient treatment of infected wounds. Biomaterials ...
Hui Ren, Zhen Zhang, Xueliang Cheng, Zheng Zou, Xuesi Chen, Chaoliang He*. Injectable, self-healing hydrogel adhesives with firm tissue adhesion and on-demand biodegradation for sutureless wound closure. Science Advances 2023, 9, eadh4327.
Dan Zhao, Yan Rong, Dong Li, Chaoliang He*, Xuesi Chen. Thermo-induced physically-crosslinked polypeptide-based block copolymer hydrogels for biomedical applications. Regenerative Biomaterials 2023, 10, rbad039.
Zhiqiang Lin, Junfeng Ding, Xuesi Chen, Chaoliang He*. pH- and temperature-responsive hydrogels based on tertiary amine-modified polypeptides for stimuli-responsive drug delivery. Chemistry - An Asian Journal 2023, 18, e202300021.
Zhixiong Chen#, Yan Rong#, Junfeng Ding, Xueliang Cheng, Xuesi Chen and Chaoliang He*. Injectable polypeptide hydrogel depots containing dual immune checkpoint inhibitors and doxorubicin for improved tumor immunotherapy and post-surgical tumo...
Dan Zhao, Dong Li, Xueliang Cheng, Zheng Zou, Xuesi Chen, Chaoliang He*. Mucoadhesive, Antibacterial, and Reductive Nanogels as a Mucolytic Agent for Efficient Nebulized Therapy to Combat Allergic Asthma. ACS Nano 2022, DOI: https://doi.org/...
Wei-Hai Chen, Qi-Wen Chen, Qian Chen, Chunyan Cui, Shun Duan, Yongyuan Kang, Yang Liu, Yun Liu, Wali Muhammad, Shiqun Shao, Chengqiang Tang, Jinqiang Wang, Lei Wang, Meng-Hua Xiong, Lichen Yin, Kuo Zhang, Zhanzhan Zhang, Xu Zhen, Jun Feng*, C...
YiTing Bai, TianRan Wang, SongLing Zhang*, XueSi Chen, ChaoLiang He*. Recent advances in organic and polymeric carriers for local tumor chemo-immunotherapy. Science China Technological Sciences 2022, 65, 1011–1028.
Junfeng Ding, Tianran Wang, Zhixiong Chen, Zhiqiang Lin, Xuesi Chen, Chaoliang He*. Enhanced antitumor chemo-immunotherapy by local co-delivery of chemotherapeutics, immune checkpoint blocking antibody and IDO inhibitor using an injectable p...
Dong Li#, Shun Shi#, Dan Zhao, Yan Rong, Yuhao Zhou, Junfeng Ding, Chaoliang He*, Xuesi Chen*. Effect of polymer topology and residue chirality on biodegradability of polypeptide hydrogels. ACS Biomaterials Science & Engineering 2022, 8(2...
Dong Li, Dan Zhao, Chaoliang He*, Xuesi Chen*. Crucial impact of residue chirality on the gelation process and biodegradability of thermoresponsive polypeptide hydrogels. Biomacromolecules 2021, 22(9), 3992-4003. DOI:10.1021/acs.biomac.1c007...
Dan Zhao, Dong Li, Fenli Quan, Yuhao Zhou, Zhen Zhang, Xuesi Chen, Chaoliang He*. Rapidly Thermoreversible and Biodegradable Polypeptide Hydrogels with Sol–Gel–Sol Transition Dependent on Subtle Manipulation of Side Groups. Biomacromolecules...
Yue Cao, Yuhao Zhou, Zhixiong Chen, Zhen Zhang, Xuesi Chen, Chaoliang He*. Localized chemotherapy based on injectable hydrogel boosts the antitumor activity of adoptively transferred T lymphocytes in vivo. Advanced Healthcare Materials 2021,...
Yuhao Zhou, Zhixiong Chen, Dan Zhao, Dong Li, Chaoliang He*, Xuesi Chen*. A pH-triggered self-unpacking capsule containing zwitterionic hydrogel-coated MOF nanoparticles for efficient oral exendin-4 delivery. Advanced Materials 2021, 33, 2102...
Yingge Shi, Dong Li, Junfeng Ding, Chaoliang He*, Xuesi Chen. Physiologically relevant pH- and temperature-responsive polypeptide hydrogels with adhesive properties. Polymer Chemistry 2021, DOI: 10.1039/d1py00290b.
Shun Shi, Jiayu Wang, Tianran Wang, Hui Ren, Yuhao Zhou, Gao Li, Chaoliang He*, Xuesi Chen. Influence of residual chirality on the conformation and enzymatic degradation of glycopolypeptide based biomaterials. Science China Technological Scie...
Yingge Shi, Dong Li, Chaoliang He*, Xuesi Chen. Design of an injectable polypeptide hydrogel depot containing the immune checkpoint blocker anti-PD-L1 and doxorubicin to enhance antitumor combination therapy. Macromolecular Bioscience 20...
Hongyu Ma, Chaoliang He*, Xuesi Chen. Injectable hydrogels as local depots at tumor sites for antitumor immunotherapy and immune-based combination therapy. Macromolecular Bioscience 2021, 21, 2100039.