研究成果

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研究成果-2024

研究成果-2024

Hui Ren, Zhen Zhang*, Kailun Lu, Yuanyuan Shen, Chaoliang He*, Xuesi Chen. Injectable chitosan hydrogels loaded with antioxidant agent as first-aid dressings for second-degree burn wounds. Science China Technological Sciences, 2024, 67(3), 89...

综述-2024

综述-2024

Jiaxuan Yang, Yan Rong,* Xuesi Chen, Chaoliang He*. Hydrogel scaffolds with controlled postgelation modulation of structures for 3d cell culture and tissue engineering. Macromolecular Chemistry and Physics 2024, 225(5), 2300365.

综述-2024

综述-2024

Hui Ren, Zhen Zhang*, Xuesi Chen, Chaoliang He*. Stimuli-responsive hydrogel adhesives for wound closure and tissue regeneration. Macromolecular Bioscience 2024, 24(3), 2300379.

研究成果-2024

研究成果-2024

Xueliang Cheng#, Zhen Zhang#, Hui Ren, Zheng Zou, Yu Zhang, Yang Qu, Xuesi Chen*, Jianwu Zhao* and Chaoliang He*. A low-swelling hydrogel as a multirole sealant for efficient dural defect sealing and prevention of postoperative adhesion. Nati...

研究成果-2024

研究成果-2024

Tianran Wang, Junfeng Ding, Shuang Liang, Zhiqiang Lin, Jiaxuan Yang, Zhen Zhang, Zheng Zou, Gao Li, Xuesi Chen, Chaoliang He*. An adhesive immune-stimulating multifunctional hydrogel for potent tumor chemoimmunotherapy and postoperative woun...

研究成果-2024

研究成果-2024

Zhen Zhang, Chaoliang He*, Xuesi Chen*. Designing hydrogels for immunomodulation in cancer therapy and regenerative medicine. Advanced Materials 2024, 36, 2308894, DOI: 10.1002/adma.202308894.

研究成果-2023

研究成果-2023

Zheng Zou, Zhen Zhang, Hui Ren, Xueliang Cheng, Xuesi Chen, Chaoliang He*. Injectable antibacterial tissue-adhesive hydrogel based on biocompatible o-phthalaldehyde/amine crosslinking for efficient treatment of infected wounds. Biomaterials ...

研究成果-2023

研究成果-2023

Hui Ren, Zhen Zhang, Xueliang Cheng, Zheng Zou, Xuesi Chen, Chaoliang He*. Injectable, self-healing hydrogel adhesives with firm tissue adhesion and on-demand biodegradation for sutureless wound closure. Science Advances 2023, 9, eadh4327.

研究成果-2023

研究成果-2023

Dan Zhao, Yan Rong, Dong Li, Chaoliang He*, Xuesi Chen. Thermo-induced physically-crosslinked polypeptide-based block copolymer hydrogels for biomedical applications. Regenerative Biomaterials 2023, 10, rbad039.

研究成果-2023

研究成果-2023

Zhiqiang Lin, Junfeng Ding, Xuesi Chen, Chaoliang He*. pH- and temperature-responsive hydrogels based on tertiary amine-modified polypeptides for stimuli-responsive drug delivery. Chemistry - An Asian Journal 2023, 18, e202300021.

研究成果-2023

研究成果-2023

Zhixiong Chen#, Yan Rong#, Junfeng Ding, Xueliang Cheng, Xuesi Chen and Chaoliang He*. Injectable polypeptide hydrogel depots containing dual immune checkpoint inhibitors and doxorubicin for improved tumor immunotherapy and post-surgical tumo...

研究成果-2022

研究成果-2022

Dan Zhao, Dong Li, Xueliang Cheng, Zheng Zou, Xuesi Chen, Chaoliang He*. Mucoadhesive, Antibacterial, and Reductive Nanogels as a Mucolytic Agent for Efficient Nebulized Therapy to Combat Allergic Asthma. ACS Nano 2022, DOI: https://doi.org/...

研究成果-2022

研究成果-2022

Wei-Hai Chen, Qi-Wen Chen, Qian Chen, Chunyan Cui, Shun Duan, Yongyuan Kang, Yang Liu, Yun Liu, Wali Muhammad, Shiqun Shao, Chengqiang Tang, Jinqiang Wang, Lei Wang, Meng-Hua Xiong, Lichen Yin, Kuo Zhang, Zhanzhan Zhang, Xu Zhen, Jun Feng*, C...

研究成果-2022

研究成果-2022

YiTing Bai, TianRan Wang, SongLing Zhang*, XueSi Chen, ChaoLiang He*. Recent advances in organic and polymeric carriers for local tumor chemo-immunotherapy. Science China Technological Sciences 2022, 65, 1011–1028.

研究成果-2022

研究成果-2022

Junfeng Ding, Tianran Wang, Zhixiong Chen, Zhiqiang Lin, Xuesi Chen, Chaoliang He*. Enhanced antitumor chemo-immunotherapy by local co-delivery of chemotherapeutics, immune checkpoint blocking antibody and IDO inhibitor using an injectable p...

研究成果-2022

研究成果-2022

Dong Li#, Shun Shi#, Dan Zhao, Yan Rong, Yuhao Zhou, Junfeng Ding, Chaoliang He*, Xuesi Chen*. Effect of polymer topology and residue chirality on biodegradability of polypeptide hydrogels. ACS Biomaterials Science & Engineering 2022, 8(2...

研究成果-2021

研究成果-2021

Dong Li, Dan Zhao, Chaoliang He*, Xuesi Chen*. Crucial impact of residue chirality on the gelation process and biodegradability of thermoresponsive polypeptide hydrogels. Biomacromolecules 2021, 22(9), 3992-4003. DOI:10.1021/acs.biomac.1c007...

研究成果-2021

研究成果-2021

Dan Zhao, Dong Li, Fenli Quan, Yuhao Zhou, Zhen Zhang, Xuesi Chen, Chaoliang He*. Rapidly Thermoreversible and Biodegradable Polypeptide Hydrogels with Sol–Gel–Sol Transition Dependent on Subtle Manipulation of Side Groups. Biomacromolecules...

研究成果-2021

研究成果-2021

Yue Cao, Yuhao Zhou, Zhixiong Chen, Zhen Zhang, Xuesi Chen, Chaoliang He*. Localized chemotherapy based on injectable hydrogel boosts the antitumor activity of adoptively transferred T lymphocytes in vivo. Advanced Healthcare Materials 2021,...

研究成果-2021

研究成果-2021

Yuhao Zhou, Zhixiong Chen, Dan Zhao, Dong Li, Chaoliang He*, Xuesi Chen*. A pH-triggered self-unpacking capsule containing zwitterionic hydrogel-coated MOF nanoparticles for efficient oral exendin-4 delivery. Advanced Materials 2021, 33, 2102...