研究成果

gain

Legumain-cleavable 4-arm poly(ethylene glycol)-doxorubicin conjugate for tumor specific delivery and release
A poly(L-glutamic acid)-combretastatin A4 conjugate for solid tumor therapy: Markedly improved therapeutic efficiency through its low tissue penetration in solid tumor
Curcumin-encapsulated polymeric nanoparticles for metastatic osteosarcoma cells treatment
Inhibiting Solid Tumor Growth In Vivo by Non-Tumor-Penetrating Nanomedicine
综述-2018

综述-2018

Shuangjiang Yu, Chaoliang He*, Xuesi Chen. Injectable hydrogels as unique platforms for local chemotherapeutics‐based combination antitumor therapy. Macromolecular Bioscience 2018, 18(12), 1800240.

Synthesis and Characterization of Star-Shaped Block Copolymer of Poly(Epsilon-Caprolactone) and Poly(Ethyl Ethylene Phosphate) as Drug Carrier.

Synthesis and Characterization of Star-Shaped Block Copolymer of Po...

Synthesis and Characterization of Star-Shaped Block Copolymer of Poly(Epsilon-Caprolactone) and Poly(Ethyl Ethylene Phosphate) as Drug Carrier. Cheng, Jing; Jian-Xun Ding; Yu-Cai Wang and Jun Wang. Polymer, 2008. 49(22), 4784-4790.

One-Step Preparation of Reduction-Responsive Poly(Ethylene Glycol)-Poly (Amino Acid)S Nanogels as Efficient Intracellular Drug Delivery Platforms.

One-Step Preparation of Reduction-Responsive Poly(Ethylene Glycol)-...

One-Step Preparation of Reduction-Responsive Poly(Ethylene Glycol)-Poly (Amino Acid)S Nanogels as Efficient Intracellular Drug Delivery Platforms. Ding, Jianxun; Fenghua Shi; Chunsheng Xiao; Lin Lin; Li Chen; Chaoliang He; Xiuli Zhuang and Xuesi ...

Preparation of Photo-Cross-Linked Ph-Responsive Polypeptide Nanogels as Potential Carriers for Controlled Drug Delivery.

Preparation of Photo-Cross-Linked Ph-Responsive Polypeptide Nanogel...

Preparation of Photo-Cross-Linked Ph-Responsive Polypeptide Nanogels as Potential Carriers for Controlled Drug Delivery. Ding, Jianxun; Xiuli Zhuang; Chunsheng Xiao; Yilong Cheng; Li Zhao; Chaoliang He; Zhaohui Tang and Xuesi Chen. Journal of Mat...

Synthesis of Amphiphilic Alternating Polyesters with Oligo(Ethylene Glycol) Side Chains and Potential Use for Sustained Release Drug Delivery.

Synthesis of Amphiphilic Alternating Polyesters with Oligo(Ethylene...

Synthesis of Amphiphilic Alternating Polyesters with Oligo(Ethylene Glycol) Side Chains and Potential Use for Sustained Release Drug Delivery. Wang, Wei; Jianxun Ding; Chunsheng Xiao; Zhaohui Tang; Di Li; Jie Chen; Xiuli Zhuang and Xuesi Chen. Bi...

Intracellular Microenvironment Responsive Pegylated Polypeptide Nanogels with Ionizable Cores for Efficient Doxorubicin Loading and Triggered Release.

Intracellular Microenvironment Responsive Pegylated Polypeptide Nan...

Intracellular Microenvironment Responsive Pegylated Polypeptide Nanogels with Ionizable Cores for Efficient Doxorubicin Loading and Triggered Release. Shi, Fenghua; Jianxun Ding; Chunsheng Xiao; Xiuli Zhuang; Chaoliang He; Li Chen and Xuesi Chen....

Glucose-Sensitive Polypeptide Micelles for Self-Regulated Insulin Release at Physiological Ph.

Glucose-Sensitive Polypeptide Micelles for Self-Regulated Insulin R...

Glucose-Sensitive Polypeptide Micelles for Self-Regulated Insulin Release at Physiological Ph. Zhao, Li; Jianxun Ding; Chunsheng Xiao; Pan He; Zhaohui Tang; Xuan Pang; Xiuli Zhuang and Xuesi Chen. Journal of Materials Chemistry, 2012. 22(24), 123...

Thermosensitive Hydrogels Based on Polypeptides for Localized and Sustained Delivery of Anticancer Drugs.

Thermosensitive Hydrogels Based on Polypeptides for Localized and S...

Thermosensitive Hydrogels Based on Polypeptides for Localized and Sustained Delivery of Anticancer Drugs. Cheng, Yilong; Chaoliang He; Jianxun Ding; Chunsheng Xiao; Xiuli Zhuang and Xuesi Chen. Biomaterials, 2013. 34(38), 10338-10347.

Biocompatible Reduction-Responsive Polypeptide Micelles as Nanocarriers for Enhanced Chemotherapy Efficacy in Vitro.

Biocompatible Reduction-Responsive Polypeptide Micelles as Nanocarr...

Biocompatible Reduction-Responsive Polypeptide Micelles as Nanocarriers for Enhanced Chemotherapy Efficacy in Vitro. Ding, Jianxun; Jinjin Chen; Di Li; Chunsheng Xiao; Jiancheng Zhang; Chaoliang He; Xiuli Zhuang and Xuesi Chen. Journal of Materi...

Efficacious Hepatoma-Targeted Nanomedicine Self-Assembled from Galactopeptide and Doxorubicin Driven by Two-Stage Physical Interactions.

Efficacious Hepatoma-Targeted Nanomedicine Self-Assembled from Gala...

Efficacious Hepatoma-Targeted Nanomedicine Self-Assembled from Galactopeptide and Doxorubicin Driven by Two-Stage Physical Interactions. Ding, Jianxun; Chunsheng Xiao; Yuce Li; Yilong Cheng; Nannan Wang; Chaoliang He; Xiuli Zhuang; Xiaojuan Zhu a...

Self-Reinforced Endocytoses of Smart Polypeptide Nanogels for "on-Demand" Drug Delivery.

Self-Reinforced Endocytoses of Smart Polypeptide Nanogels for "on-D...

Self-Reinforced Endocytoses of Smart Polypeptide Nanogels for "on-Demand" Drug Delivery. Ding, Jianxun; Weiguo Xu; Ying Zhang; Diankui Sun; Chunsheng Xiao; Donghong Liu; Xiaojuan Zhu and Xuesi Chen. Journal of Controlled Release, 2013. 172(2), 44...

Thermo-Responsive "Hairy-Rod" Polypeptides for Smart Antitumor Drug Delivery.

Thermo-Responsive "Hairy-Rod" Polypeptides for Smart Antitumor Drug...

Thermo-Responsive "Hairy-Rod" Polypeptides for Smart Antitumor Drug Delivery. Ding, Jianxun; Li Zhao; Di Li; Chunsheng Xiao; Xiuli Zhuang and Xuesi Chen. Polymer Chemistry, 2013. 4(11), 3345-3356.

The Synthesis, Deprotection and Properties of Poly(Gamma-Benzyl-L-Glutamate).

The Synthesis, Deprotection and Properties of Poly(Gamma-Benzyl-L-G...

The Synthesis, Deprotection and Properties of Poly(Gamma-Benzyl-L-Glutamate). Han, Jindong; Jianxun Ding; Zhichun Wang; Shifeng Yan; Xiuli Zhuang; Xuesi Chen and Jingbo Yin. Science China-Chemistry, 2013. 56(6), 729-738.

Polymeric Topology and Composition Constrained Polyether-Polyester Micelles for Directional Antitumor Drug Delivery.

Polymeric Topology and Composition Constrained Polyether-Polyester ...

Polymeric Topology and Composition Constrained Polyether-Polyester Micelles for Directional Antitumor Drug Delivery. Li, Di; Hai Sun; Jianxun Ding; Zhaohui Tang; Ying Zhang; Weiguo Xu; Xiuli Zhuang and Xuesi Chen. Acta Biomaterialia, 2013. 9(11),...

Facile One-Pot Synthesis of Glucose-Sensitive Nanogel Via Thiol-Ene Click Chemistry for Self-Regulated Drug Delivery.

Facile One-Pot Synthesis of Glucose-Sensitive Nanogel Via Thiol-Ene...

Facile One-Pot Synthesis of Glucose-Sensitive Nanogel Via Thiol-Ene Click Chemistry for Self-Regulated Drug Delivery. Zhao, Li; Chunsheng Xiao; Jianxun Ding; Pan He; Zhaohui Tang; Xuan Pang; Xiuli Zhuang and Xuesi Chen. Acta Biomaterialia, 2013....

Noncovalent Interaction-Assisted Polymeric Micelles for Controlled Drug Delivery.

Noncovalent Interaction-Assisted Polymeric Micelles for Controlled ...

Noncovalent Interaction-Assisted Polymeric Micelles for Controlled Drug Delivery. Ding, Jianxun; Linghui Chen; Chunsheng Xiao; Li Chen; Xiuli Zhuang and Xuesi Chen. Chemical Communications, 2014. 50(77), 11274-11290