研究成果-2022
YiTing Bai, TianRan Wang, SongLing Zhang*, XueSi Chen, ChaoLiang He*. Recent advances in organic and polymeric carriers for local tumor chemo-immunotherapy. Science China Technological Sciences 2022, 65, 1011–1028.
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YiTing Bai, TianRan Wang, SongLing Zhang*, XueSi Chen, ChaoLiang He*. Recent advances in organic and polymeric carriers for local tumor chemo-immunotherapy. Science China Technological Sciences 2022, 65, 1011–1028.
Junfeng Ding, Tianran Wang, Zhixiong Chen, Zhiqiang Lin, Xuesi Chen, Chaoliang He*. Enhanced antitumor chemo-immunotherapy by local co-delivery of chemotherapeutics, immune checkpoint blocking antibody and IDO inhibitor using an injectable p...
Dong Li#, Shun Shi#, Dan Zhao, Yan Rong, Yuhao Zhou, Junfeng Ding, Chaoliang He*, Xuesi Chen*. Effect of polymer topology and residue chirality on biodegradability of polypeptide hydrogels. ACS Biomaterials Science & Engineering 2022, 8(2...
Dong Li, Dan Zhao, Chaoliang He*, Xuesi Chen*. Crucial impact of residue chirality on the gelation process and biodegradability of thermoresponsive polypeptide hydrogels. Biomacromolecules 2021, 22(9), 3992-4003. DOI:10.1021/acs.biomac.1c007...
Dan Zhao, Dong Li, Fenli Quan, Yuhao Zhou, Zhen Zhang, Xuesi Chen, Chaoliang He*. Rapidly Thermoreversible and Biodegradable Polypeptide Hydrogels with Sol–Gel–Sol Transition Dependent on Subtle Manipulation of Side Groups. Biomacromolecules...
Yue Cao, Yuhao Zhou, Zhixiong Chen, Zhen Zhang, Xuesi Chen, Chaoliang He*. Localized chemotherapy based on injectable hydrogel boosts the antitumor activity of adoptively transferred T lymphocytes in vivo. Advanced Healthcare Materials 2021,...
Yuhao Zhou, Zhixiong Chen, Dan Zhao, Dong Li, Chaoliang He*, Xuesi Chen*. A pH-triggered self-unpacking capsule containing zwitterionic hydrogel-coated MOF nanoparticles for efficient oral exendin-4 delivery. Advanced Materials 2021, 33, 2102...
Yingge Shi, Dong Li, Junfeng Ding, Chaoliang He*, Xuesi Chen. Physiologically relevant pH- and temperature-responsive polypeptide hydrogels with adhesive properties. Polymer Chemistry 2021, DOI: 10.1039/d1py00290b.
Shun Shi, Jiayu Wang, Tianran Wang, Hui Ren, Yuhao Zhou, Gao Li, Chaoliang He*, Xuesi Chen. Influence of residual chirality on the conformation and enzymatic degradation of glycopolypeptide based biomaterials. Science China Technological Scie...
Yingge Shi, Dong Li, Chaoliang He*, Xuesi Chen. Design of an injectable polypeptide hydrogel depot containing the immune checkpoint blocker anti-PD-L1 and doxorubicin to enhance antitumor combination therapy. Macromolecular Bioscience 20...
Hongyu Ma, Chaoliang He*, Xuesi Chen. Injectable hydrogels as local depots at tumor sites for antitumor immunotherapy and immune-based combination therapy. Macromolecular Bioscience 2021, 21, 2100039.
Zhen Zhang, Chaoliang He*, Yan Rong, Hui Ren, Tianran Wang, Zheng, Zou, Xuesi Chen*. A fast and versatile cross-linking strategy via o-phthalaldehyde condensation for mechanically strengthened and functional hydrogels. National Science ...
Yuhao Zhou, Liang Liu, Yue Cao, Shuangjiang Yu, Chaoliang He*, Xuesi Chen*. A nanocomposite vehicle based on metal-organic framework nanoparticle incorporated biodegradable microspheres for enhanced oral insulin delivery. ACS Applied Materia...
Yan Rong, Zhen Zhang, Chaoliang He*, Xuesi Chen. Bioactive polypeptide hydrogels modified with RGD and N-cadherin mimetic peptide promote chondrogenic differentiation of bone marrow mesenchymal stem cells. Science China Chemistry 2020 , 63...
Shun Shi, Shuangjiang Yu, Gao Li*, Chaoliang He*, Xuesi Chen. Biocompatible in situ-forming glycopolypeptide hydrogels. Science China Technological Sciences 2020, 63(6), 992-1004.
Zhen Zhang , Chaoliang He *, and Xuesi Chen * , Injectable Click Polypeptide Hydrogels via Tetrazine-Norbornene Chemistry for Localized Cisplatin Release . Polymers 2020, 12, 884 ;
（26） 一种喷砂处理的控制系统. 孙志强;庞烜;李帅;张涵;陈文啟;陈学思. CN201710707241.3 （25） 一种烯醇式锌化合物、其制备方法及其作为催化剂的应用. 庞烜;段然龙;杨警卫;张瑜;孙志强;梁源;陈学思. CN201710427793.9 （24） 一种希夫碱铁化合物、其制备方...
Molecular Strings Significantly Improved the Gene Transfection Efficiency of Polycations，Fang Huapan, Guo Zhaopei, Lin Lin, Chen Jie, Sun Pingjie, Wu Jiayan, Xu Caina, Tian Huayu, Chen Xuesi，Journal of the American Chemical Society 2018, 140(3...
(116) Ding, X.; Li, G.; Zhang, P.; Xiao, C.*, Constructing Thermally Reversible Dynamic Hydrogels via Catalysis-Free Knoevenagel Condensation. ACS Macro Letters 2020, 9, 830-835. (115) She, P.; Bian, S.; Cheng, Y.; Dong, S.*; Liu, J.*; Liu...