研究成果

gain

Bortezomib Increases the Cancer Therapeutic Efficacy of Poly(amino acid −Doxorubicin
Combretastatin A4 Nanoparticles Combined with Hypoxia-Sensitive Imiquimod: A New Paradigm for the Modulation of Host Immunological Responses during Cancer Treatment
Glucose and pH Dual-Responsive Nanogels for Effcient Protein Delivery
Hypoxia-sensitive supramolecular nanogels for the cytosolic delivery of ribonuclease A as a breast cancer therapeuti
Selectively Potentiating Hypoxia Levels by Combretastatin A4 Nanomedicine: Toward Highly Enhanced Hypoxia-Activated Prodrug Tirapazamine Therapy for Metastatic Tumors
Neutralizing tumor-promoting inflammation with polypeptide-dexamethasone conjugate for microenvironment modulation and colorectal cancer therapy
Rationally Designed Polymer Conjugate for Tumor-Specific Amplification of Oxidative Stress and Boosting Antitumor Immunity
Combretastatin A4 nanodrug combined plerixafor for inhibiting tumor growth and metastasis simultaneously
Combretastatin A4 Nanodrug-Induced MMP9 Amplifcation Boosts Tumor-Selective Release of Doxorubicin Prodrug
111

111

研究成果-2018

研究成果-2018

Yilong Cheng, Chaoliang He*, Kaixuan Ren, Yan Rong, Chunsheng Xiao, Jianxun Ding, Xiuli Zhuang, Xuesi Chen*. Injectable enzymatically cross-linked hydrogels with light-controlled degradation profile. Macromolecular Rapid Communications&n...

研究成果-2017

研究成果-2017

Xilong Wu, Yundi Wu, Hongbo Ye, Shuangjiang Yu, Chaoliang He*, Xuesi Chen*. Interleukin-15 and cisplatin co-encapsulated thermosensitive polypeptide hydrogels for combined immuno-chemotherapy. Journal of Controlled Release 2017, 255, 81-...

研究成果-2017

研究成果-2017

Shuangjiang Yu, Dianliang Zhang, Chaoliang He*, Wujin Sun, Rangjuan Cao, Shusen Cui, Mingxiao Deng, Zhen Gu*, Xuesi Chen*. Injectable Thermo-Sensitive Polypeptide-based CDDP-Complexed Hydrogel for Improving Localized Antitumor Efficacy. Bioma...

研究成果-2017

研究成果-2017

Kaixuan Ren, Bin Li, Qinghua Xu, Chunsheng Xiao, Chaoliang He*, Gao Li*, Xuesi Chen. Enzymatically Crosslinked Hydrogels based on Linear Poly(ethylene glycol) Polymer: Performance and Mechanism. Polymer Chemistry 2017, 8(45), 7017-7024.

研究成果-2017

研究成果-2017

Qinghua Xu, Zhen Zhang, Chunsheng Xiao, Chaoliang He*, Xuesi Chen*. Injectable polypeptide hydrogel as biomimetic scaffolds with tunable bioactivity and controllable cell adhesion. Biomacromolecules 2017, 18 (4), 1411-1418.

综述-2016

综述-2016

Chaoliang He, Zhaohui Tang, Huayu Tian, Xuesi Chen*. Co-delivery of chemotherapeutics and proteins for synergistic therapy. Advanced Drug Delivery Reviews 2016, 98, 64-76.

研究成果-2016

研究成果-2016

Xilong Wu, Chaoliang He*, Yundi Wu, Xuesi Chen*. Synergistic therapeutic effects of Schiff's base cross-linked injectable hydrogels for local co-delivery of metformin and 5-fluorouracil in a mouse colon carcinoma model. Biomaterials 2016, 75,...

研究成果-2016

研究成果-2016

Qinghua Xu, Chaoliang He*, Zhen Zhang, Kaixuan Ren, Xuesi Chen*. Injectable, biomolecule-responsive polypeptide hydrogels for cell encapsulation and facile cell recovery through triggered degradation. ACS Applied Materials & Interfaces&nb...

研究成果-2016

研究成果-2016

Kaixuan Ren, Haitao Cui, Qinghua Xu, Chaoliang He*, Gao Li*, Xuesi Chen. Injectable polypeptide hydrogels with tunable microenvironment for 3D spreading and chondrogenic differentiation of bone marrow-derived mesenchymal stem cells. Biomacrom...

研究成果-2016

研究成果-2016

Qinghua Xu, Chaoliang He*, Kaixuan Ren, Chunsheng Xiao, Xuesi Chen*. Thermosensitive polypeptide hydrogels as a platform for ROS-triggered cargo release with innate cytoprotective ability under oxidative stress. Advanced Healthcare Materials&...