研究成果

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Combretastatin A4 Nanodrug-Induced MMP9 Amplifcation Boosts Tumor-Selective Release of Doxorubicin Prodrug
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研究成果-2018

研究成果-2018

Yilong Cheng, Chaoliang He*, Kaixuan Ren, Yan Rong, Chunsheng Xiao, Jianxun Ding, Xiuli Zhuang, Xuesi Chen*. Injectable enzymatically cross-linked hydrogels with light-controlled degradation profile. Macromolecular Rapid Communications&n...

研究成果-2017

研究成果-2017

Xilong Wu, Yundi Wu, Hongbo Ye, Shuangjiang Yu, Chaoliang He*, Xuesi Chen*. Interleukin-15 and cisplatin co-encapsulated thermosensitive polypeptide hydrogels for combined immuno-chemotherapy. Journal of Controlled Release 2017, 255, 81-...

研究成果-2017

研究成果-2017

Shuangjiang Yu, Dianliang Zhang, Chaoliang He*, Wujin Sun, Rangjuan Cao, Shusen Cui, Mingxiao Deng, Zhen Gu*, Xuesi Chen*. Injectable Thermo-Sensitive Polypeptide-based CDDP-Complexed Hydrogel for Improving Localized Antitumor Efficacy. Bioma...

研究成果-2017

研究成果-2017

Kaixuan Ren, Bin Li, Qinghua Xu, Chunsheng Xiao, Chaoliang He*, Gao Li*, Xuesi Chen. Enzymatically Crosslinked Hydrogels based on Linear Poly(ethylene glycol) Polymer: Performance and Mechanism. Polymer Chemistry 2017, 8(45), 7017-7024.

研究成果-2017

研究成果-2017

Qinghua Xu, Zhen Zhang, Chunsheng Xiao, Chaoliang He*, Xuesi Chen*. Injectable polypeptide hydrogel as biomimetic scaffolds with tunable bioactivity and controllable cell adhesion. Biomacromolecules 2017, 18 (4), 1411-1418.

综述-2016

综述-2016

Chaoliang He, Zhaohui Tang, Huayu Tian, Xuesi Chen*. Co-delivery of chemotherapeutics and proteins for synergistic therapy. Advanced Drug Delivery Reviews 2016, 98, 64-76.

研究成果-2016

研究成果-2016

Xilong Wu, Chaoliang He*, Yundi Wu, Xuesi Chen*. Synergistic therapeutic effects of Schiff's base cross-linked injectable hydrogels for local co-delivery of metformin and 5-fluorouracil in a mouse colon carcinoma model. Biomaterials 2016, 75,...

研究成果-2016

研究成果-2016

Qinghua Xu, Chaoliang He*, Zhen Zhang, Kaixuan Ren, Xuesi Chen*. Injectable, biomolecule-responsive polypeptide hydrogels for cell encapsulation and facile cell recovery through triggered degradation. ACS Applied Materials & Interfaces&nb...

研究成果-2016

研究成果-2016

Kaixuan Ren, Haitao Cui, Qinghua Xu, Chaoliang He*, Gao Li*, Xuesi Chen. Injectable polypeptide hydrogels with tunable microenvironment for 3D spreading and chondrogenic differentiation of bone marrow-derived mesenchymal stem cells. Biomacrom...

研究成果-2016

研究成果-2016

Qinghua Xu, Chaoliang He*, Kaixuan Ren, Chunsheng Xiao, Xuesi Chen*. Thermosensitive polypeptide hydrogels as a platform for ROS-triggered cargo release with innate cytoprotective ability under oxidative stress. Advanced Healthcare Materials&...

综述-2016

综述-2016

Qinghua Xu, Chaoliang He*, Chunsheng Xiao, Xuesi Chen*. Reactive oxygen species (ROS) responsive polymers for biomedical applications. Macromolecular Bioscience 2016, 16(5), 635-646.

综述-2016

综述-2016

Zhaohui Tang, Chaoliang He, Huayu Tian, Jianxun Ding, Benjamin S Hsiao*, Benjamin Chu, Xuesi Chen*. Polymeric nanostructured materials for biomedical applications. Progress in Polymer Science 2016, 2016, 60, 86-128.

研究成果-2015

研究成果-2015

Kaixuan Ren, Chaoliang He*, Chunsheng Xiao, Gao Li*, Xuesi Chen. Injectable glycopolypeptide hydrogels as biomimetic scaffolds for cartilage tissue engineering. Biomaterials 2015, 51, 238-249.

研究成果-2015

研究成果-2015

Qinghua Xu, Chaoliang He*, Chunsheng Xiao, Shuangjiang Yu, Xuesi Chen*. ε-methacryloyl-L-Lysine based polypeptides and their thiol-ene click functionalization. Polymer Chemistry 2015, 6(10), 1758-1767.

研究成果-2015

研究成果-2015

Xilong Wu, Chaoliang He, Yundi Wu, Xuesi Chen*, Jianjun Cheng*. Nanogel-incorporated physical and chemical hybrid gels for highly effective chemo-protein combination therapy. Advanced Functional Materials 2015, 25 (43), 6744-6755.

研究成果-2014

研究成果-2014

Kaixuan Ren, Chaoliang He*, Yilong Cheng, Gao Li*, Xuesi Chen. Injectable enzymatically crosslinked hydrogels based on a poly(L-glutamic acid) graft copolymer. Polymer Chemistry 2014, 5(17), 5069-5076.

研究成果-2014

研究成果-2014

Shuangjiang Yu, Jianxun Ding, Chaoliang He*, Yue Cao, Weiguo Xu, Xuesi Chen. Disulfide cross-linked polyurethane micelles as a reduction-triggered drug delivery system for cancer therapy. Advanced Healthcare Materials 2014, 3(5), 752-760.

研究成果-2013

研究成果-2013

Xiaoye Gao, Yue Cao, Xiangfu Song, Zhe Zhang, Chunsheng Xiao, Chaoliang He*, Xuesi Chen. pH- and thermo-responsive poly(N-isopropylacrylamide-co-acrylic acid derivative) copolymers and hydrogels with LCST dependent on pH and alkyl side groups...